In a recent podcast interview, Seth Rogen confirmed that Anne Hathaway dropped out of the 2007 hit comedy 'Knocked Up' due to reservations about a particular scene - the birth sequence. Initially cast as Alison Scott, Hathaway opted out when she found the birthing scene too explicit for her taste. Rogen recalled that Hathaway didn't want the delivery to be visually graphic, a decision he respects. Interestingly, the role was eventually taken by Katherine Heigl, who delivered her baby in a less graphic manner. Despite this, Hathaway's decision seems to have been vindicated as the film's history shows she was right about more things than Rogen over the years! In past interviews, Hathaway has clarified that she turned down the part due to the explicit nature of the birth scene, and she has also addressed her clean-cut image by stating her comfort with on-camera nudity. She has previously appeared nude in films like 'Havoc' and 'Brokeback Mountain'. The podcast episode can be heard on The A24 Podcast, with Rogen discussing various aspects of his career, including the role that kickstarted his fame - Knocked Up.